Clinical Statistician
Full time - Permanent position (CDI)

About Pharnext
Pharnext ( is an advanced clinical-stage biopharmaceutical company developing novel therapeutics for orphan and common neurodegenerative diseases that currently lack curative and/or disease-modifying treatments. Pharnext has two lead products in clinical development. PXT3003 completed an international Phase 3 trial with positive results for the treatment of Charcot-Marie-Tooth disease type 1A and was given orphan drug status in Europe and the United States. PXT864 has generated encouraging Phase 2 results in Alzheimer’s disease. Pharnext has developed a new drug discovery paradigm based on big genomic data and artificial intelligence: PLEOTHERAPY™. Pharnext identifies and develops synergic combinations of drugs called PLEODRUG™. The Company was founded by renowned scientists and entrepreneurs including Professor Daniel Cohen, pioneer in genomics, and is supported by a world-class scientific team.

The Pharnext Data Science Department is looking for a highly motivated senior statistician with a deep experience of clinical trial.


  • Clinical activities
    • Coordinate clinical programmers (intern and extern).
    • Write statistical analyses plans, statistical reports and review CSR.
    • Write and maintain clinical statistical SOP.
    • Participate in data review activities (eCRF, blind review…).
    • Implement statistical analyses.
    • Maintain up-to-date programming solutions in line with industry requirements.
    • Guarantee compliance of the statistical analyses with respect to the scientific direction of the department.
  • Scientific activities
    • Propose new and innovative statistical methods.
    • Propose and coordinate post-hoc statistical analyses.
    • Stay up-to-date in clinical statistics methods via regular literature reviews.
    • Participate in the writing of scientific publications.

Ph.D. in Statistics applied to Health Sciences with an additional 5 years’ experience in industry-oriented Clinical Statistics.

  • Excellent mastery of theorical statistics.
  • Knowledge of R and SAS are mandatory.
  • Good knowledge of the ICH and CDISC standards are mandatory.
  • Good understanding of regulatory requirements relevant to Statistical Programming.
  • Critical thinking, autonomy, multitasking and ability to team-work and communicate in English and French.

You are highly motivated with a strong profile in industry-oriented clinical statistics and health sciences. You enjoy working in an interdisciplinary and international environment to contribute to the development of novel therapies against orphan and common diseases, send:

  • A full CV
  • A motivation letter (max. 2 pages)

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11-13 rue René Jacques
92130, Issy les Moulineaux